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Treatment of Early Yiqiyangyin blood diabetic nephropathy

; 0.05). The two groups were compared before and after treatment UAE Table l,[link widoczny dla zalogowanych], the two groups after treatment than before treatment UAE increased significantly (P <0.05), and the UAE to improve the rate of the treatment group was significantly higher (P <0.05) . Table 1 groups the UAE before and after treatment comparison (mg/24h, fork ± s) Note: with this group before treatment, P <0.05; compared with the control group after treatment. △ P <0.05, () the data of the number, the same below. Table 2 before and after treatment blood glucose, blood lipid changes compared (mmol / L. Fork ± S) two groups of patients before and after the blood glucose and lipid changes in Table 2. Treatment group, FBG, PBG, TG, TC after treatment than before treatment significantly improved (P <0.05), · 448 · addition to TC, the other three were better than the control group (P <0.05). FBG control group after treatment than before treatment had improved (P <0.05), the other three before and after treatment no significant difference. Effective follow-up of patients treated were followed up for 0.5 years l7 cases, including l5 patients with symptomatic, UAE stability, l patient had no patients who continued medication, clinical improvement, UAE decreased. Adverse events before and after treatment both groups without liver and kidney dysfunction, course of treatment no adverse reactions. 4 Discussion IDN into the mechanism of genetic factors in most current and long-term high blood glucose, lipid metabolism disorders and other environmental factors interact, the glomerular blood flow, filtration rate (GFR) and pressure increased, renal ischemia, hypoxia , protein non-enzymatic glycation, polyol pathway activation and oxidative stress. The persistence of these abnormalities result in mesangial matrix and glomerular basement membrane synthesis and degradation of mesangial matrix and basement membrane decreased, resulting in glomerular sclerosis. DN emphasis on early diagnosis and early treatment, once the progression to clinical nephropathy stage, the renal pathological changes irreversible, clinical treatment of IDN in an ideal state of DM control, limiting protein intake, common ACEI agents have protective effects on the kidneys, delay the occurrence of kidney disease and reduce microalbuminuria. IDN but only have a certain effect, clinical observations show that the Western identified the combination of disease and efficacy of TCM will be better. In medicine: DN of the many for the kidney, IDN is more developed on the basis of diabetes Yin Deficiency, unable to transport blood deficiency, yin deficiency and blood incomprehensible, blood running sluggish and stasis, in turn, stressed the gas deficiency loss at the same time, more attention to end stasis. IDN clinical manifestations of patients rely on blood stasis as Qi and Yin Deficiency. Therefore, nourishing blood used for the method, Fang, Astragalus, of Gan, tepid, qi and yin, and blood stagnation line, thirst, nourishing Insufficiency of the gas; so busy in order to promote blood gas, blood stasis and not to hurt the positive, and help the power of various drugs, King and medicine. Modern pharmacology that: Astragalus main role is to vasodilators, lowering blood pressure, increased renal blood flow, reduce platelet adhesion rate, improve microcirculation, which is rich in selenium, on the glomerular basement membrane charge barrier and mechanical barriers have protection, thereby reducing the permeability proteinuria. Abnormalities may improve regional blood flow dynamics to reduce or delay the progress】 IDN. Angelica of sweet, bitter, acrid, warm, blood and blood; Chuanxiong, peach kernel, safflower, blood, qi, meridians; Rehmannia nourishing yin, the benefits of the essence; dogwood ney Yigan; wolfberry benefits smart head; yam AIDS Kidney Spleen: Alisma Rehmannia and diarrhea with renal Jiangzhuo; Poria infiltration with yam and spleen wet; Modern pharmacological studies have shown that: a hypoglycemic effect Poria, Alisma have reduced the role of total cholesterol and triglyceride; ginseng sexual Gan, Ping, lungs, large Rotary strength; Ophiopogon, Digupi of sweet, cold, hot and Chufan Qing Xu, Yin Sheng Jin; Schisandra acid, convergence Guse, Qi, Sheng Jin. Sharing of various drugs, played a total of Activating Blood and the power, and produce better clinical efficacy. Clinical observations show that: nourishing blood can improve the clinical symptoms, regulating blood glucose, urinary albumin excretion rate continued to improve.