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Bronchial artery infusion and systemic chemotherapy in advanced lung cancer evaluation

Advanced lung cancer, developed rapidly in recent years, t and achieved satisfactory clinical efficacy of our hospital from April 1988 to August 1993 for the 144 back bronchial artery infusion chemotherapy for the A group, of which 117 cases were plus low-dose systemic chemotherapy for the B group. 44 down over the same period the amount of intravenous systemic chemotherapy as the big Jing c group. Before treatment, all the sick were clear cytological diagnosis. Adopted by the Fourteenth Meeting of the TNM method of lung cancer are in the advanced category. Treatment program: A group: cisplatin or carboplatin 600rag + 60mg mitomycin 12rag. B: infusion solutions and a small dose of t with A group of programs with C,[link widoczny dla zalogowanych], C group, a dose of 112 ~ 113. C: small cell carcinoma: carboplatin 400rag/in · the first day of infusion, epirubicin 40mg / m. , The first day of intravenous, Vp a 16100mg 3 to 7 days intravenous infusion. Non-small cell carcinoma; cyclophosphamide 600 ~ 800mg / m, the first day of epirubicin 40rag/111 intravenous cisplatin 50rng 3 to 5 days Jing Li River above options are for a course around the second week after infusion of small of. Results 1. Term effect in accordance with international and domestic common chemotherapy evaluation criteria tCR: complete remission; PR: partial remission Is: stable IP: progress. Each group in Table 1. Wrapped in a recent observation i do not last CR () PR () s () p () A271 (3.7) 5 (18.5) 18 (66.6) 3 (11.1) B11714 (11.1) 47 (40.1) 51 (43.5) 5 (4.2) C441 (2.2) 10 (22.7) 14 (31.8) 19 (43.1) statistical results suggest that: A group was effective (CRPR) 22.2, the total effective rate was 88.9; B group was 52.1r markedly effective rate was 95.7. 5O tumor size more than lame gone down t atelectasis ease, metastatic lymph nodes to reduce t create the conditions for elective surgery effective rate of 25 C Group, the total effective rate was 56.8 compared three groups, B group was better than the other two groups, on the superior vena cava syndrome, atelectasis are especially effective to improve t. B group the degree of toxicity of group A close,[link widoczny dla zalogowanych], but much lighter than C group according to WHO toxicity of anticancer drugs classificatory criteria, bone marrow suppression C group, 38 down, I degree of reaction of 60.5. l ° 10.5; B group 98 degrees 8.1Il degrees down tJ 1; A group l8 down, I was 16.7 degrees,[link widoczny dla zalogowanych], no l degrees reaction. None of the three groups Ⅳ magic bone marrow suppression. The impact of transaminase A, B groups to a lesser extent, gastrointestinal response to the high incidence of C group, the degree saddle weight. A group of local drug treatment can swollen laugh and systemic drug concentration is high concentration of low 0]. If surgery supplemented by l, 2 ~ 1 / 3 of the same amount of body venous billion thistle treatment, can improve the curative effect and to control cancer metastasis. 2. Long-term effect: Long-term effect this election case there are three tracks: ① the hospital for observation; ② clinic I @ letters. A total of 92 patients were followed up. The last follow-up to August 1993, were lost by death count (Table 2). Three groups are not the ideal long-term outcome]. After only a few ill surgical reperfusion Yu, survived for 2 to 4 years. B group, the median survival and survival is not very different with the A group compared c t but there are still differences. Wrapped 2 to discuss long-term efficacy of factors affecting efficacy, this article prompted tA, B group of central type lung cancer treatment than your good peripheral, solitary lesions are more effective lesions Gao Jia, the value is not obvious in the C group. Diffuse bilateral lung disease, C group slightly better. Metastatic lung cancer efficacy of the three groups were lower, suggesting that comprehensive treatment of lung cancer Taiwan is still the best choice. In summary, B group in the treatment of advanced lung cancer, with recent good effect. Toxic reaction to light,[link widoczny dla zalogowanych], less painful chemotherapy, the high quality of life, illness, etc. A willing to accept, is effective in the treatment of advanced lung cancer is one reference to Wen Jing Yan 1 He Guohui precision of the diagnosis and treatment of swollen Nanchang Jiangxi Science and Technology published by Du-1990I78. z · Pang Qiqing t other bronchial artery infusion chemotherapy drugs inserted bud 82 advanced lung cancer down swollen wall of China Journal, 1989t11t60.3 · Guoji Xuan t and so on. Of lung cancer with bronchial moving hot filling to evaluate the efficacy of chemotherapy in short and long term - the fifth world conference proceedings compiled lung cancer. Beijing 1993:90 - (Received: 1994 More articles related to topics：

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