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Acute cholestatic hepatitis clinical observation of 64 cases

2 (2002) 06-0525-01 acute cholestatic hepatitis in 64 patients observed Shih, Deng Ying (1. North China University of Medical College Hospital, Jilin 132011; 2. Anorectal Hospital in Jilin City, Jilin 132011) Abstract: clinical observations, cholestatic hepatitis were older, more women than men, have jaundice, there are different degrees of obstructive jaundice presentation, treatment is difficult, longer duration, chronic trend. Key words: cholestatic hepatitis; jaundice; chronic CLC number: R512.6 Document code: A1 recent clinical data in all cases are infected patients hospitalized for acute 2a cholestatic hepatitis patients, 7 were males and females 57 cases, the oldest 74 years old, minimum 42 years old, mean age (56 ± 14) years of age, all cases diagnosed are in line with the 1995 National Conference on Infectious and Parasitic Diseases revised the Deeper level of 64 cases of patients had varying degrees of jaundice and pruritus, lighter colored stool of obstructive jaundice such as performance, the majority of cases, fatigue, loss of appetite, nausea, tired oil symptoms, hepatomegaly in 20 cases, all cases of liver function levels in Table 1. Table 164 cases of patients with cholestatic liver conditions liver hepatitis average p (ALF) / (U · L-1) 10 (AST) / (U · L-1) c (TBIL) / (vtmol · L) c (DBIL) / (vtmol · L) p (r-GT) / (U · L) p (ALK) / (U · L-1) 478 ± 130285 ± 146280 ± 136150 ± 125580 ± 170180 ± 100 All cases were done A, B, C, D, E, hepatitis G virus pathogenic markers, which found positive for hepatitis B virus markers in 2 cases, hepatitis C virus markers positive in 1 case, 1 case was positive for hepatitis E virus markers, The remaining 60 cases were negative for pathogen detection. After clinical treatment, 50 cases cured. Cure criteria: clinical symptoms and signs disappeared, liver function returned to normal, and the remaining 14 patients hospitalized for various reasons are not systematic treatment, including treatment time up to 4 months, the shortest one half months, an average of 2 months. Can be followed up in the 16 patients, 6 patients found to have recurrent disease, persistent jaundice more than 6 months, to chronic liver disease. 2, 64 patients were discussed, the average age of onset (56 ± 14) years of acute hepatitis E than the average age of onset is larger .... And the incidence of women far more than men, in all cases except 4 cases detected in the B, C, hepatitis E virus markers, the rest were negative, so the incidence of cholestatic hepatitis unclear reasons, possibly related to J and autoimmune . Way for the dissemination of disease incidence in both elderly women. From the clinical point of view, all patients had jaundice, 100%, and the degree of jaundice deep fade for a long time, have varying degrees of skin itching, stool color lighter so the performance of obstructive jaundice, liver function point of view, r-GT,[link widoczny dla zalogowanych], ALK elevated levels are higher. In the treatment point of view, than other types of hepatitis treatment for a long time, applications are generally lower xanthate results are poor, can be used to reduce prostaglandin E yellow treatment. Can be followed up in 16 patients, 6 cases become chronic, indicating that the higher trend of chronic disease, could evolve into primary biliary cirrhosis, because this article can be fewer cases of follow-up to convince poor future cases to be expanded to strengthen the follow-up, should also be checked for their immunization to further observational study