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Insulin resistance,[link widoczny dla zalogowanych], pancreatic β cell function of the impact of gestational diabetes

As covariates,[link widoczny dla zalogowanych], and compares AI. A16'J / AG6'J. HOMA-B cell function index difference between the 3 groups asked; 3 groups asked the force 'analysis of variance,[link widoczny dla zalogowanych], P <0.05, a P <0. O1. ... P <0.001 and the pathogenesis of GDM. Normal and GDM pregnant women during pregnancy were significantly increased insulin secretion. Pregnant 3. The relationship between insulin secretion and GDM: AI60/AG60 from NGT to IGT, GDM gradual decline (Table 2, P <O.0131). GDM cases △ I60 / △ G60 are few compared with the NGT, decreased 53% (e'e, P <0.05); HOMA-p cell function index progressively from NGT to GDM is decreasing (Table 2). Visible, GDM group compared with NGT, impaired insulin secretion. Third, to discuss the study excluded the possibility of pre-pregnancy BMI and gestational age under the influence of IR and p cell dysfunction in gestational diabetes in the role. 1. The relationship between IR and GDM occurred: the increase of pregnant women with gestational age, placental secretion of insulin action against the increasing number of hormones, and insulin resistance in parallel increasing. This is a The IR results showed higher than normal pregnant women, GDM patients, more than the third trimester of physiological insulin resistance. GDM women also suggest additional potential and insulin resistance may be chronic. ¨ Buchanan and other studies have considered the existence of two GDM patients may be insulin resistance, a normal third trimester pregnant women, the performance of began to show significant late, and can be extended to post-partum. The results of this study agreed with them. 2. 13 islet cell dysfunction and the relationship between the occurrence of GDM: In this study, △ I60, AI60/AG6o, and HOMA-B cell function index comprehensive evaluation of insulin secretion, results suggest that GDM women with normal third trimester pregnant women, p cell function is decreased in comparison The. The incidence of GDM and impaired insulin secretion is also related. Advanced up to the highest. In a sense, the level of individual B cell function were assessed during pregnancy out more. IR increase during pregnancy, B cells to IR the compensatory ability of individual differences to be displayed and amplification, B cell function in women with low high blood sugar may occur suffering GDM. Can be seen, GDM and type 2 diabetes pathogenesis are similar only in B cell function is impaired insulin secretion when combined with existing IR, GDM will occur. GDM pregnant women could explain this incidence rate is 1% to 5%, not most or all pregnant women.