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Xiayuxue Decoction on lipid peroxidation in liver cirrhosis and its intervention

Dimension of the change in the main, a small number of false lobules formed to split off the normal lobular lobular lobular common fake, fat necrosis of the more obvious changes, showing acidophilic bodies, to point-like, focal necrosis common, rare necrosis See and inflammatory cell infiltration. General observation in liver medicine with western medicine group of basic, see the white nodules up to 0.1cm: microscopic pathological changes similar to the situation with the western medicine group, but the necrotic fat lighter. Reference [2] method of liver fibrosis, liver fibrosis and cirrhosis in each group formed in Table 6. Table 6 groups the formation of liver fibrosis and cirrhosis Note: 0 is no fibrosis: I level for the portal area or central veins around the fiber mild hyperplasia, II level: significant fibrosis,[link widoczny dla zalogowanych], a separate trend; III level: False lobule,[link widoczny dla zalogowanych], there are definite cirrhosis. 4, the results can be seen from the above discussion Xiayuxue decoction on hepatic fibrosis, to prevent liver cirrhosis, compared with the control group, expressed as HA, Ⅳ a C content is low, mild liver fibrosis, cirrhosis of the liver caused by external factors under the constant, the time required for the formation of long cirrhosis, the formation of cirrhosis of the liver is low, and the formation of cirrhosis of the liver mainly as split pseudolobuli,[link widoczny dla zalogowanych], showing changes of early liver cirrhosis [3], its anti-hepatic fibrosis to prevent the degree of cirrhosis of the liver similar to colchicine. Liver cirrhosis is constantly degeneration, necrosis, re-conversion process, the present study, CCI and the liver against ethanol induced liver cirrhosis, and lipid peroxidation involved in the process of which, the performance of the prototype for the antioxidant glutathione also peptide (GSH-PX) decreased lipid peroxidation (LPO) increased. Lipid peroxidation can lead to liver cell membrane damage, the liver causing inflammation and fibrosis of the important conditions, LPO production to reactive oxygen species ((ROS) increase, increased toxicity, and inhibition of antioxidant system, promoting the development of the lesion [4] . Xiayuxue observed in this study, soup can interfere with lipid peroxidation, GSH-PX showed higher and the LPO than the control group. At the same time, indicators of liver damage ALT, Y-GT, HA, IV-C and the histologic fibrosis of liver degeneration and necrosis of the control was significantly better than the control group. Xiayuxue prompted the Intervention Role of lipid peroxidation is a mechanism for preventing cirrhosis of the liver. From the above results Medicines can be seen, although western medicine group with similar levels of hepatic fibrosis, but the intervention of lipid peroxidation, reduce mortality and improve quality of life and aspects of liver Liver better than Western medicine group medicine group. Is this prompt: ① In the process of liver fibrosis may prevent a variety of ways,[link widoczny dla zalogowanych], interfere with lipid peroxidation is only one of the mechanisms to prevent cirrhosis of the liver; ② in the choice of medication, not only to note the role of cirrhosis of the liver,[link widoczny dla zalogowanych], but also pay attention to the overall functional improvements. colchicine group of defects may be linked to colchicine toxicity. (get the whole experiment 98 Hospital of PLA, with the help of comrades Mayi Jiang, grateful to.)