www.public4you.fora.pl

90nike5657fv

,[link widoczny dla zalogowanych]
Breast cancer patients with LEP,[link widoczny dla zalogowanych], IGF-1 and TNFα Determination and clinical significance

2O 5 on No. 1 LaboratoryMedicine2005. v0l20. N01 complete management package by SPSS10.0. Results In the normal control group, serum LEP,[link widoczny dla zalogowanych], IGF. 1 and TNFc ~ concentrations and breast cancer difference between groups was significant (P 0.05), see Table 1, Table 2. Table 1 in benign and malignant breast disease group and control group serum LEP, IGF. 1, TNFa levels (-4-s) Note: Compared with normal control group,[link widoczny dla zalogowanych],} P <0.05; with benign breast disease group, # P <O. 05 Table 2 axillary lymph node status in breast cancer patients with serum LEP, IGF. 1, TNFot level (-4-s) Note: with and without lymph node metastasis group,} P <0.05 has been discussed, obesity is considered a risk factor for breast cancer, and women have a tendency to obesity in patients breast cancer, the disease potential danger, and poor prognosis. The results also show that the breast cancer group and control group BMI value and the difference between benign breast disease group there were significant (P <0.05). With further research on obesity and the development of molecular biology techniques, obesity, ob gene was successfully cloned, and its encoded protein product - LEP was found. Found in breast epithelial cells and receptor expression have LEPmRNA, LEP can increase the normal breast cell proliferation, increased breast cancer cell proliferation, suggesting that LEP may be related to the occurrence of breast cancer J. LEP to promote breast cancer cell growth mechanism may: LEP through autocrine and systemic endocrine effect on mammary epithelial cells, promoting tumor cell growth, but also promote tumor invasion to the surrounding tissue to enhance the incidence of tumor blood vessels to promote fat organization androstadienone conversion to estrone, which interact with estrogen to stimulate breast epithelial hyperplasia to breast tumors J. Our results in breast cancer serum LEP was significantly higher than the normal control group, and benign breast disease group and control group no significant difference between; lymph node metastasis of breast cancer serum level was significantly higher than that of LEP lymph node metastasis breast cancer group. IGF is a class of multifunctional cell proliferation regulatory factors, mainly in the blood involved in many types of cell proliferation, growth. In breast cancer cells, IGF as follows: (1) early breast cancer can occur IGF. 1 levels, IGF. 1 levels and malignant phenotype of breast cancer-related; (2) high concentrations of IGF. 1 promotes the proliferation and metastasis of breast cancer cells, inhibit breast cancer cell apoptosis. The results of this study, the breast cancer serum IGF-1 levels were significantly higher than the other two groups, serum IGF-1 in breast cancer patients without axillary lymph node levels significantly correlated between. TNF is a by monocytes. Macrophages produced cytokines, have anti-tumor cells. The results showed that breast cancer group and benign breast disease group was significantly lower than serum TNFc ~ normal control group, while the breast cancer group and benign breast disease group no significant difference between. Therefore, the detection of breast cancer patients with serum IGF-1, LEP, TNFc ~ concentration, helps to determine the status of breast lesions.
More articles related to topics：

MAC Cosmetics UK 反复性自发流产与淋巴细胞主动免疫

Tory Burch Outlet Superior mesenteric artery blood

ray ban occhiali 耳穴埋药促产褥早期乳汁分泌的观察_