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Herpes simplex keratitis immune pathogenesis

M]. Philadelphia: Lippincott / Williams & Wilkins. 2001.2399-246019EverettRD. ICPO,[link widoczny dla zalogowanych], aregulatorofherpessimplexvirusduringlyricandlatentinfection [J]. Bioessays ,2000,22:761-77020MulveyM, PoppersJ, SternbergD, eta1. RegulationofelF2aphosphorylationbydifferentfunctionsthatactduringdiscretephasesintheherpessimplexvirustype1lifecycle [J]. JVirol, 2003. 77:1 O917-10928 (a l8 Received :2006-06 Revised :2006-12-26) (This article Editor: Hu Pure Steel) benzene poisoning visual retrobulbar neuritis case Yangzhi Rui Guo Shouzhi Electrophysiological characteristics of patients, Female, 18 years old, due to decline in both eyes, hearing loss associated with more than 10 days, on January 15, 2002 to our hospital. The patient is a hand-painted metal toy toy factory paint dye workers in a poorly ventilated environment, described the paint in hand painted four months. Patients with previous good health, sight, hearing were normal. Treatment in patients with bilateral hearing loss when the body check,[link widoczny dla zalogowanych], I was no exception. Head CT revealed no abnormalities. Eye examination: both eyes, 0.1, can not be correct, the pupil diameter of 4.0mm, direct light reflex sluggish. Check the eyes and see the end of the optic disc hyperemia, fuzzy boundaries, retinal vascular thin, reflective foveal less clear. Line pattern visual evoked potential (P-VEP) and flash electroretinogram (F-ERG) examination, using the German Roland Corporation RETIporG2 visual electrophysiology system, in accordance with international clinical visual electrophysiology proposed international standard for inspection. P-VEP examination showed: right eye P. . . Wave latency is 130ms, left eye P. . . Wave latency is 128ms,[link widoczny dla zalogowanych], significantly longer than normal. Volatility is low. F. ERG dark-adapted rod cell response, dark-adapted maximal response, oscillatory potentials (OPs), cone light adaptation responses and light adaptation flicker of light were within normal range. Diagnosed as chronic benzene poisoning retrobulbar optic neuritis. Into the ear because of hearing loss in patients with consultation, double check the integrity of the eardrum, the light cone light reflex normal. Pure tone audiometry left ear air conduction band is 82dB, bone 67dB, right ear air conduction as 72dB, bone 62dB, ears to listen to wisdom) Author: 054001 Xingtai City Eye Hospital Ophthalmology (Yang Zhirui), ENT (Guoshou Corresponding author: Yang Zhirui (Email: [link widoczny dla zalogowanych]) · case report showed a flat threshold curve. Acoustic impedance tests show the left ear was A, the right ear drum was c-type pressure tympanograms, stapedius reflex not elicited, cross-acoustic reflection 1kHz, ears are 120dBHL, 500Hz, 2kHz, 4kHz when not elicited. The patient had occupational diseases by the Beijing Chaoyang Hospital, Medical Research Center and diagnosed with toxic benzene poisoning. discussion: benzene can cause damage to the hematopoietic system optic nerve ischemia, hypoxia circulation and metabolism, resulting in optic nerve damage, eye showed decreased visual acuity, optic disc hyperemia, fuzzy boundaries, reflecting less clear macular center. an early manifestation of inflammation or retrobulbar optic neuritis symptoms, advanced stage optic nerve atrophy. benzene poisoning is rare retrobulbar optic neuritis, the patients due to poor ventilation conditions in the hand described in the painting after painting 4 months decreased visual acuity, probably due to benzene and its metabolites on the nervous system damage,[link widoczny dla zalogowanych], optic and auditory nerve damage caused. VEP reflects the retinal ganglion cells to bio-electrical activity of the visual cortex, these pathways can lead to damage on the VEP abnormalities, therefore, VEP testing can help early diagnosis of optic neuropathy, and can detect lesions dynamic process. Foreign long-term exposure of gasoline, printing and dyeing, paint and other chemicals benzene workers VEP detection, display P... wave amplitude decreased, the peak potential to extend, with the patient test results are similar, but no country relevant reports. VEP in the performance of patients meet the performance characteristics of optic nerve damage, but the disease is diagnosed to be combined with history. (Received :2006-11-10) (This article Editor: Yin Weijing)
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