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After penetrating keratoplasty and cyclosporin A reasonable application of corticosteroids

j1JCJinXV. AmJOphthalmologyl! I95119} 18;: 6] ChienAM, SchmldtCM. CohenE'J. ... 1AmJOphthalmology2o-2f Eye Hospital, Xingtai City, Hebei Province 0540011993l15; 7l1 (73Arma [yMF, ArchOphthalmology196777: 747 [8] LewisJM.Prlddyr.JuddJ.etalAmJOphthalmology1088l06: 607L19 Origin of a close】 pretty eyes.. Death of epiphyseal white. Crystal protein allergy glaucoma 15 cases, / Dan limonene Lan fell £ mileage prime cotton Guoyue Xia Dong Kun peaks Wu heroes Zhang Weihong / ~-77v, 3 crystal protein allergy Majesty glaucoma (Phac0anaphy1act1cglaucoma) is due to the crystal material allergy caused endophthalmitis lead angle damage to reports on secondary glaucoma less now in our department from May 1994 to] 999 in April l5 encountered patients (23 eyes) reported the following: clinical information, general information: 15 cases, 9 were male and (14 eyes) and 6 female patients (9 eyes). aged 9 to 75 years old, average 50.65 years of which 4 cases of traumatic cataract in 5 eyes (3 eyes had cataract extraction surgery), cataract extraction after 3 Example 5 eyes, extracapsular cataract extraction and intraocular lens implantation in 2 patients 3. senile cataract overripe Pi 2 eyes of 1 patient, the crystal nuclear cataract surgery in 1 case of vitreous body falling A 2, spontaneous absorption of the crystal 4 cases 6, II, eye conditions: 1. acuity (corrected vision) in 4 eyes with no light perception. light perception to hand in 6 eyes, the immediate index .0.02 to 0.01 by 3 ~ 0. 08 4 eyes .0.1 ~ 0.6 in 6 eyes. 2. intraocular pressure intraocular pressure by hand with all the repair're's tonometer measured. IOP 3.44kPa ~ l1.73kPa (1kPa a 7. 5mmHg). Average 5.64kPa ± 2.] 4kPa3. 23 eyes of 16 other cases had corneal haze. Almost all patients had varying amounts of possession of a white suet-like KP, room flash (X), 8 anterior chamber a large number of inflammatory exudate .4 glaucomatous eye fundus changes occurred. All the patients were cytology water intercourse, the results can be seen lymphocytes and macrophages, in some cases can also see a small amount of pigment epithelial cells and fibrin-like l2 cases of physical blood test has detected a higher IgA and IgM. 4 眼 pathology reports are as follows: The anterior segment was inflammatory changes color film,[link widoczny dla zalogowanych], the crystal is surrounded by granulomatous inflammation, its asking spotty macrophages, plasma cell lymphocytes and epithelioid cells three,[link widoczny dla zalogowanych], treatment: 23 eyes of six lines and some residual cortical lens vitrectomy, in which l eye surgery to remove artificial crystal; a line of crystal cortex aspiration technique; two intracapsular cataract extraction surgery: a 4 by the drug treatment is difficult to control intraocular pressure, glaucoma and retinal changes occur. the purposes of the filtering surgery; 4 without the sense of vision underwent enucleation; more than six ho given to conservative treatment. 13 cases before and after treatment in patients with both local and base body applications corticosteroids, 2 cases were patients with topical application of dexamethasone IV apparatus, followed up time: 1 to 49 months, the average l8.25-month results of 23 eyes treated except 4 enucleation outside. the other 19 eyes were treated with a drug or surgical therapy treatment significantly reduced corneal calm things. anterior chamber inflammation reduced corrected visual acuity improved in varying degrees. which 9 visual acuity of> 0.3. Treatment IOP changes before and after the Annex. One must point 8 eyes treated with timolol eye drops 0.5 twice a day. 4 glaucoma surgery, 2 eyes were the eyes of follicles is not obvious. Despite Local massage and plus 0.5 timolol eye drops twice a day, IOP control is not satisfactory. With the proverb in the process of relapse in 3 cases in 5 eyes, because patients do not agree to schedule surgery to conservative treatment before and after treatment I11 / ~ (soil s-XkPa) discussed changes in protein crystals is a typical allergic eye glaucoma autoimmune disease (auto-immunediseaseAID). its target antigen for immunization is mainly soluble protein crystals. now detect hidden crystal contains 20 kinds of antigens can be considered immune original base. human lens proteins, including a, 8,[link widoczny dla zalogowanych], three, within the crystal structure of proteins. Among the most crystal protein antigen. epitopes with some other body cells, mitochondria , endoplasmic reticulum,[link widoczny dla zalogowanych], actin filaments and nuclei have cross-antigenicity
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