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Cardiac sarcoplasmic lightly stained fibers, the nucleus disappears. Leaving only a small number of red particles showed degeneration and necrosis of the state. Mild interstitial capillary congestion. 3 Discussion It has been reported Cynanchum toxic alkaloids, there is a strong irritant to the skin by a large dose of topical (skin dose) to make white blood poisoning occurs L5]. According to Xing Xu and other agricultural Cynanchum reported the acute toxicity of alkaloids,[link widoczny dla zalogowanych], alkaloids of LD. . To 164.0 ± 10. 5mg/kg; the time of death in mice after administration, total alkaloids and extended with the dose reduced (0.5 ~ 24h) L6]. I set this test dose of 300mg/kg of test animals die result is in line with this report. In I, I group were fed doses of 300mg/kg, 600mg/kg, based on the results of death in mice,[link widoczny dla zalogowanych], Ⅲ, Ⅳ groups were fed doses of 30mg/kg, 60mg/kg. Death within 15 days of group Ⅲ, Ⅳ group died within 1 week, confirmed that the total alkaloid Cynanchum strong toxicity. The number of the mice in this experiment is limited, so there is no determination of LD. . . Alkaloids of Cynanchum mainly heart, lungs, kidneys, toxic effects of different levels, which can be seen that the total alkaloids from Cynanchum the main target organ is the heart, lung and kidney, as to whether Cynanchum also toxic to other tissues and organs, further studies need to be verified. Therefore,[link widoczny dla zalogowanych], grazing pastures in the deserts, especially when the year is dry, we should pay attention to the poisoning of Cynanchum livestock disease control; in recent years,[link widoczny dla zalogowanych], the study of medicinal Cynanchum more L7], in the Cynanchum As a medicinal plant resource development at the same time, its side effects should also be given some attention.
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